Identifying asynchronies: Reverse trigger

Víctor Perez, Jamille Pasco

Cite

Perez V, Pasco J. Identifying asynchronies: Reverse trigger. J Mech Vent 2022; 3(2):88-91.

Abstract

A variety of asynchronies between the patient’s respiratory efforts and the programed ventilatory settings have been categorized.

Reverse trigger is described as an inspiratory effort occurring after a ventilator-initiated breath and may represent a form of respiratory entrainment.  In other words, the ventilator triggers muscular efforts. It often appears in a repetitive, stereotyped pattern.

It occurs often in mechanically ventilated patients at risk of injury, might be underrecognized at the bedside and may has adverse effects on oxygenation and ventilation, as well as potentially increasing lung injury.

We can phenotype these events using the Campbell diagram (pressure–volume loop) by differentiating their occurrence during inspiration and expiration.

Reverse trigger with sufficient inspiratory effort and duration can result in an additional ventilator-delivered stacked breath, which can cause large tidal volumes and increased transpulmonary pressure.

Keywords

Patient-Ventilator Asynchrony, reverse trigger, entrainment, lung injury, phenotype

Abstract

1. Telias I, Shing LK, Beitler JR. Reverse triggering, the rhythm dyssynchrony: potential implications for lung and diaphragm protection. Am J Respir Crit Care Med 2021; 203(1):5-6.
https://doi.org/10.1164/rccm.202008-3172ED
PMid:32841572 PMCid:PMC7781145
2. Kondili E, Prinianakis G, Georgopoulos D. Patient-ventilator interaction. Br J Anaesth 2003; 91(1):106-119.
https://doi.org/10.1093/bja/aeg129
PMid:12821570
3. Thille AW, Rodriguez P, Cabello B, et al. Patient-ventilator asynchrony during assisted mechanical ventilation. Intensive Care Med 2006; 32:1515-1522.
https://doi.org/10.1007/s00134-006-0301-8
PMid:16896854
4. Pham T, Telias I, Piraino T, et al. Asynchrony consequences and management. Crit Care Clin 2018; 34:325-341.
https://doi.org/10.1016/j.ccc.2018.03.008
PMid:29907268
5. Mireles-Cabodevila E, Siuba MT, Chatburn RL. A Taxonomy for patient-ventilator interactions and a method to read ventilator waveforms. Respir Care 2022; 67(1):129-148.
https://doi.org/10.4187/respcare.09316
PMid:34470804
6. Mellado Artigas R, Damiani F, Piraino T, et al. Reverse Triggering Dyssynchrony 24 h after Initiation of Mechanical Ventilation. Anesthesiology 2021; 134:760-769.
https://doi.org/10.1097/ALN.0000000000003726
PMid:33662121
7. Akoumianaki E, Lyazidi A, Rey N, et al. Mechanical ventilation-induced reverse-triggered breaths: a frequently unrecognized form of neuromechanical coupling. Chest 2013; 143:927-938.
https://doi.org/10.1378/chest.12-1817
PMid:23187649
8. Baedorf Kassis E, Su HK, Graham AR, et al. Reverse trigger phenotypes in acute respiratory distress syndrome. Am J Respir Crit Care Med 2021; 203(1):67-77.
https://doi.org/10.1164/rccm.201907-1427OC
PMid:32809842 PMCid:PMC7781129
9. Yoshida T, Nakamura M, Morais C, et al. Reverse triggering causes an injurious inflation pattern during mechanical ventilation. Am J Respir Crit Care Med 2018; 198:1096-1099.
https://doi.org/10.1164/rccm.201804-0649LE
PMid:29953244
10. Gea J, Zhu E, Gáldiz J, et al. Functional consequences of eccentric contractions of the diaphragm. Arch Bronconeumol 2009; 45:68-74.
https://doi.org/10.1016/j.arbres.2008.04.003
PMid:19232267