Split-ventilation for more than one patient, can it be done? Yes

Ehab G. Daoud, Robert Cabbat, Jewelyn Cabigan, Gary Kaneshiro, Kimiyo Yamasaki

Cite

Daoud EG, Cabbat R, Cabigan J, Kaneshiro G, Yamasaki K. Split-ventilation for more than one patient, can it be done? Yes. J Mech Vent 2020; 1(1):1-7.

Abstract

Background

The COVID-19 pandemic crisis has led to an international shortage of mechanical ventilation. Due to this shortfall, the surge of increasing number of patients to limited resources of mechanical ventilators has reinvigorated the interest in the concept of split ventilation or co-ventilation (ventilating more than one patient with the same ventilator). However, major medical societies have condemned the concept in a joint statement for multiple reasons.

Materials and Methods

In this paper, we will describe the history of the concept, what is trending in the literature about it and along our modification to ventilate two patients with one ventilator. We will describe how to overcome such concerns regarding cross contamination, re-breathing, safely adjusting the settings for tidal volume and positive end expiratory pressure to each patient and how to safely monitor each patient.

Main results

Our experimental setup shows that we can safely ventilate two patients using one ventilator.

Conclusion

The concept of ventilating more than one patient with a single ventilator is feasible especially in crisis situations. However, we caution that it has to be done under careful monitoring with expertise in mechanical ventilation. More research and investment are crucially needed in this current pandemic crisis.

Keywords

COVID-19, mechanical ventilation, Split-Ventilation, differential ventilation, respiratory failure

References

1. John Hopkins University of Medicine Corona virus resource center. https://coronavirus.jhu.edu. last accessed August 2020
2. Sommer DD , Fisher JA, Ramcharan V, et al. Improvised automatic lung ventilation for unanticipated emergencies. Crit Care Med 1994; 22(4):705-709.
https://doi.org/10.1097/00003246-199404000-00029
3. Neyman G, Irvin CB. A single ventilator for multiple simulated patients to meet disaster surge. Acad Emerg Med. 2006; 13(11):1246-1249.
https://doi.org/10.1197/j.aem.2006.05.009
PMid:16885402 PMCid:PMC7164837
4. Paladino L, Silverberg M, Charchaflieh JG, et al. Increasing ventilator surge capacity in disasters: ventilation of four adult-human-sized sheep on a single ventilator with a modified circuit. Resuscitation. 2008; 77(1):121-126.
https://doi.org/10.1016/j.resuscitation.2007.10.016
PMid:18164798
5. Branson RD, Blakeman TC, Robinson BR, et al. Use of a single ventilator to support 4 patients: laboratory evaluation of a limited concept. Respir Care 202; 57(3):399-403.
https://doi.org/10.4187/respcare.01236
PMid:22005780
6. Menes K, Tintinalli J, Plaster L. How one Las Vegas ED saved hundreds of lives after the worst mass shooting in US history. Emergency Physicians Monthly. November 3, 2017
7. Society of Critical Care medicine. https://www.sccm.org/Disaster/Joint-Statement-on-Multiple-Patients-Per-Ventilator/ last accessed August 2020
8. American Association of Respiratory Care. https://www.aarc.org/joint-statement-guidance-document-on-multiple-patients-per-ventilator/ last accessed August 2020
9. White DB, Lo B. A Framework for Rationing Ventilators and Critical Care Beds During the COVID-19 Pandemic. JAMA 2020; 323(18):1773-1774.
https://doi.org/10.1001/jama.2020.5046
PMid:32219367
10. Chu Q, Correa R, Henry TL, et al. Reallocating ventilators during the coronavirus disease 2019 pandemic: Is it ethical? Surgery 2020; S0039-6060(20)30254-3.
https://doi.org/10.1016/j.surg.2020.04.044
PMid:32616345 PMCid:PMC7205622
11. Department of health and human services. https://www.hhs.gov/about/news/2020/03/31/optimizing-ventilator-use-during-covid19-pandemic.html. Published March 2020, last accessed August 2020.
12. Food and Drug Administration. Emergency Use Authorization – FDA. https://www.fda.gov/media/136423/download Published March 2020, last accessed August 2020
13. Columbia University College of Physicians & Surgeons. Ventilator Sharing Protocol: Dual-Patient Ventilation with a Single Mechanical Ventilator for Use during Critical Ventilator Shortages. Published March 2020, last accessed August 2020
14. Chatburn RL, Branson RD, Hatipog˘lu U. Multiplex Ventilation: A simulation-based Study of ventilating 2 patients with a single ventilator. Respir Care 2020; 65(7):920-931.
https://doi.org/10.4187/respcare.07882
PMid:32345741
15. Clarke AL, Stephens AF, Liao S, et al. Coping with COVID-19: ventilator splitting with differential driving pressures using standard hospital equipment. Anesthesia 2020, 75:872-880.
https://doi.org/10.1111/anae.15078
PMid:32271942 PMCid:PMC7262199